Research
Hormonal
If access to GLP-1RAs was restricted to people with severe obesity and 50% moved into a lower BMI category, there would be a simulated reduction in cumulative cancer cases of 7476.
Restricting GLP-1RA access to those with severe obesity can still lead to significant cancer case reductions.
StrongSupportsmedium confidence
If access to GLP-1RAs was restricted to people with severe obesity and 50 % of people with severe obesity moved into a lower BMI category, there was a simulated reduction in cumulative cancer cases of 7476.
Why this rating
Based on the simulation model described in the abstract.
Source
Impact of GLP-1 receptor agonist-induced weight loss on 22 cancers in the next ten years using a Markov state-transition model – A UK weight and wellness cancer landscape analysis
Jiawen Dong et al. · Cancer Epidemiology · 2025
DOI 10.1016/j.canep.2025.102837
otherCited 3×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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