Research
The literature, read and rated
Getting lean isn't a mystery, it's a settled question buried under noise. So I read the science: thousands of findings pulled from peer-reviewed papers, each rated for how strong the evidence is and traced back to its source. No opinions, no hype, just what the studies actually show, with the source on every claim so you can check it yourself.
- 28k
- findings catalogued
- 21k
- rated strong or good
- 13k
- source papers
New in the corpus
Newest first- 2026Tirzepatide, a dual GIP/GLP-1 receptor agonist, produces significant, dose-dependent weight loss and HbA1c reduction in overweight and obese adults with type 2 diabetes, with efficacy increasing at doses of 5mg, 10mg, and 15mg administered once weekly.HormonalStrong
- 2026Tirzepatide use is associated with a significantly higher incidence of adverse reactions, particularly nausea and diarrhea, which are dose-dependent and increase with higher doses (15mg).HormonalStrong
- 2026Tirzepatide administration significantly reduces body weight in overweight and obese individuals (BMI ≥28 kg/m²) compared to control, with the magnitude of weight loss being dose-dependent.HormonalStrong
- 2026Tirzepatide significantly reduces HbA1c levels in individuals with Type 2 Diabetes, with the effect being dose-dependent.HormonalStrong
- 2026Tirzepatide use is associated with a significantly increased incidence of adverse reactions, particularly gastrointestinal issues like nausea and diarrhea, which are dose-dependent.HormonalStrong
Challenge the noise
By mechanism
- Hormonal9.0k
Insulin, leptin, thyroid, the signals behind hunger and storage.
- Energy balance5.6k
Calories in vs out — the master lever.
- Mixed4.2k
Claims spanning multiple mechanisms.
- Adherence2.8k
The behaviours that make a plan actually stick.
- Macro partitioning1.7k
Where the calories go: muscle vs fat.
- Cellular1.2k
What happens inside the cell.
- Micronutrients & recovery1.2k
The inputs that keep the system running.
- Metabolic adaptation1.1k
How the body fights back as you diet.
- Neural582
Appetite, reward, and the brain's role.
- Molecular360
Pathways at the molecular level.