Research
Hormonal
Increased residual gastric content can persist up to 10 days after stopping subcutaneous semaglutide.
Clinicians may need to consider longer pre-operative interruption intervals for patients on semaglutide to reduce aspiration risk.
StrongSupportsmedium confidence
The finding by Nersessian et al. that increased residual gastric content can persist up to 10 days after stopping subcutaneous semaglutide is important.
Why this rating
The study is based on an observational cohort design with a significant sample size.
Source
Gastric point‐of‐care ultrasound in the GLP‐1 receptor agonist era: clinical impact and competency
Dáire N. Kelly et al. · Anaesthesia · 2025
DOI 10.1111/anae.16548
cohort · n=220Cited 3×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
- Patients receiving semaglutide within 10 days of surgery have a significantly increased risk of residual gastric content compared to a control sample (40% vs. 3%).Strong
- Increased residual gastric content was observed regardless of whether patients held semaglutide for 1–7 or 8–10 days pre-operatively.Strong
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