Hormonal
Higher visceral adiposity, quantified by the Lipid Accumulation Product (LAP), is strongly associated with an increased risk of declined renal function (eGFR < 60 mL/min/1.73m2) in the general population, independent of traditional risk factors like diabetes and hypertension.
To protect your kidney function, focus on reducing visceral fat, not just total body weight. Use the Lipid Accumulation Product (LAP) concept: combine your waist circumference with your Triglyceride levels. A high LAP score indicates higher visceral fat and a significantly higher risk of kidney dysfunction, even if your BMI is normal. Managing this requires lifestyle interventions like caloric restriction and physical activity to lower both waist size and triglycerides.
Our findings showed that LAP strongly associated with declined renal function and could be one of markers for predicting the risk of renal dysfunction in the general Chinese population.
Why this rating
Large sample size (n=10,012) and rigorous adjustment for confounders, but the cross-sectional design prevents establishing causality.
Source
Visceral adiposity and renal function: an observational study from SPECT-China
Kun Zhang et al. · Lipids in Health and Disease · 2017
DOI 10.1186/s12944-017-0597-0
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