Hormonal

GLP-1 RA initiation was associated with a reduced incidence rate of alcohol use disorders (AUD) post RYGB (1.1% vs. 1.8%) with a hazard ratio of 0.77.

Practitioners may consider GLP-1 RAs as a strategy to reduce AUD in patients post RYGB.

StrongSupportsmedium confidence

GLP-1 RA initiation was associated with a reduced incidence rate of AUD versus control (1.1% vs. 1.8%) (HR 0.77, [95% CI: 0.549-0.840, p = 0.041]).

Olanrewaju Adeniran et al. · Obesity · 2025

Why this rating

Based on a multicenter retrospective cohort study design.

Source

Alcoholic Use Disorder Outcomes After <scp>Roux‐en‐Y</scp> Gastric Bypass in Patients Taking <scp>GLP</scp>‐<scp>1 RAs</scp>: A Multicenter Analysis

Olanrewaju Adeniran et al. · Obesity · 2025

cohort · n=6876Cited 2×

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