Research
Hormonal
Leptin levels significantly decline following semaglutide treatment, particularly in the obesity group (-5.10 ng/mL).
Semaglutide may help lower leptin levels, which could be beneficial for weight management in diabetic patients.
StrongSupportsmedium confidence
Leptin levels remained unchanged after metformin but significantly declined following semaglutide treatment (p < 0.05).
Why this rating
The study design supports the reliability of the findings.
Source
Effect of Semaglutide Add-on to Metformin on Visceral Adiposity Index and Markers of Visceral Adipose Tissue Activity in Type 2 Diabetic Patients
Abid Shaheer et al. · Biomedical & Pharmacology Journal · 2025
other · n=90Cited 1×
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