Research

Metabolic adaptation

The lower-carbohydrate or lower-GI diets increased HDL-C by about 4% and lowered triglycerides (TG) by 20% compared to the higher-carbohydrate, higher-GI diet.

Practitioners may consider recommending lower-carbohydrate or lower-GI diets to improve HDL-C and reduce triglycerides in overweight adults.

StrongSupportsmedium confidence
The lower-carbohydrate or lower-GI diets increased HDL-C by about 4% (with between diet P-values <0.016) and lowered TG by 20% (P<0.031, compared to the higher-carbohydrate, higher-GI diet).
Frank M. Sacks et al. · Circulation · 2013

Why this rating

Based on the randomized controlled trial design.

Source

Abstract 016: Effect of Dietary Carbohydrate (Amount and Type) on Risk Factors for Cardiovascular Disease and Diabetes: The OmniCarb Trial

Frank M. Sacks et al. · Circulation · 2013

DOI 10.1161/circ.127.suppl_12.a016

rct · n=163
Read the paper
DOI resolved against Crossref · corpus check 2026-06-10

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