Research
Hormonal
Tirzepatide increases HOMA-β and decreases HOMA-IR in T2D patients.
Tirzepatide may be effective in improving insulin sensitivity and β-cell function in T2D management.
StrongSupportsmedium confidence
In T2D patients, tirzepatide improved glycemic control, reduced insulin demand, increased HOMA-β, and decreased HOMA-IR.
Why this rating
The study includes clinical data from T2D patients.
Source
Tirzepatide improves pancreatic β-cell function in mice and patients with type 2 diabetes
Zhehui Li et al. · bioRxiv (Cold Spring Harbor Laboratory) · 2026
other
Read the paper This is one finding among thousands. Every one is graded and traced to its source, so you can see what the evidence actually supports. Browse the research →