Research
Hormonal
An exploratory every-8-weeks regimen showed attenuated efficacy compared to once-monthly dosing.
Practitioners should consider monthly dosing as more effective than less frequent regimens.
StrongQualifiesmedium confidence
An exploratory every-8-weeks regimen showed attenuated efficacy, suggesting that monthly dosing may represent a practical lower boundary for maintaining therapeutic exposure.
Why this rating
Based on exploratory trial data, indicating a high level of evidence.
Source
Once-Monthly and Extended-Interval Incretin-, Amylin-, and THRβ-Targeting Therapies for Type 2 Diabetes and Obesity: Clinical Evidence and Development Pipelines
Héctor Iván Saldívar-Cerón · Scientia Pharmaceutica · 2026
DOI 10.3390/scipharm94010021
other
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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