Research
Hormonal
Adaptive thermogenesis is associated with significant hormonal changes, specifically decreased leptin and T3, and reduced resting heart rate.
Low leptin and T3 levels are expected during a cut and contribute to metabolic slowdown. This is a normal hormonal response to energy deficit.
GoodSupportsHIGH confidence
Absolute leptin levels decreased in both sexes (p<0.001)... These changes occurred with similar decreases in T3 (p<0.001) and resting heart rate (p<0.01) in both sexes.
Why this rating
Clear hormonal measurements and statistical significance.
Source
Weight loss induces changes in adaptive thermogenesis in female and male physique athletes
Ville Isola et al. · Applied Physiology Nutrition and Metabolism · 2023
DOI 10.1139/apnm-2022-0372
cohort · n=48Cited 21×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
- Intensive weight loss via energy restriction and increased aerobic exercise induces adaptive thermogenesis (reduced resting energy expenditure beyond mass loss predictions) in both male and female physique athletes.Good
- Male physique athletes lose significantly more lean mass than female athletes during competition preparation, despite similar reductions in fat mass and muscle size.Good
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