Research
Hormonal
Tirzepatide was associated with greater weight loss compared with semaglutide, with a median weight loss of 8.60% vs 5.62%, P = 0.023.
Clinicians may prefer tirzepatide over semaglutide for better weight loss outcomes.
StrongSupportsmedium confidence
Tirzepatide was associated with greater weight loss compared with semaglutide (8.60% vs 5.62%, P = 0.023).
Why this rating
The study is a retrospective cohort analysis with a significant sample size.
Source
Magnitude and Determinants of Weight Loss Response to GLP-1/GIP Receptor Agonists in India: A Real-World Time-to-Event Analysis
Godana Jarso et al. · Indian Journal of Endocrinology and Metabolism · 2026
DOI 10.4103/ijem.ijem_1085_25
cohort · n=150
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
- Participants without type 2 diabetes (T2D) achieved significantly greater weight loss than those with T2D, with a median weight loss of 11.21% vs 5.48%, P < 0.001.Strong
- Younger age, tirzepatide use, and GLP1 treatment naivety were identified as determinants of faster achievement of ≥10% weight loss.Strong
Related findings · Hormonal
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