Research
Hormonal
Tirzepatide was associated with greater weight loss compared with semaglutide, with a median weight loss of 8.60% vs 5.62%, P = 0.023.
Clinicians may prefer tirzepatide over semaglutide for better weight loss outcomes.
StrongSupportsmedium confidence
Tirzepatide was associated with greater weight loss compared with semaglutide (8.60% vs 5.62%, P = 0.023).
Why this rating
The study is a retrospective cohort analysis with a significant sample size.
Source
Magnitude and Determinants of Weight Loss Response to GLP-1/GIP Receptor Agonists in India: A Real-World Time-to-Event Analysis
Godana Jarso et al. · Indian Journal of Endocrinology and Metabolism · 2026
cohort · n=150
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