Research
Hormonal
GLP-1 receptor agonists achieve clinically significant weight loss of 15–22.5% total body weight.
GLP-1 RAs can be considered effective options for achieving significant weight loss in obesity management.
StrongSupportsmedium confidence
These medications achieve clinically significant weight loss of 15–22.5% total body weight.
Why this rating
The claim is based on a synthesis of current evidence presented in the review.
Source
Obesity management medications for the surgeon
Matthew Harris et al. · Frontline Gastroenterology · 2026
review
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