Research
Hormonal
Insulin resistance compromises the body's normal response to insulin, leading to multiple diseases including Type 2 diabetes mellitus.
Practitioners should recognize insulin resistance as a critical factor in managing metabolic diseases.
StrongSupportsmedium confidence
Insulin resistance is the biological phenomenon in which the human body's normal response to the metabolic hormone insulin is compromised.
Why this rating
The abstract summarizes a review of established knowledge.
Source
Insulin Resistance: An Update on Biochemical and Pathophysiological Mechanisms and Impact on Various Diseases
Peter J. Little et al. · iNew Medicine · 2026
review
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