Research
Hormonal
The multivariate adjusted relative risk of CHD was 1.51 among women reporting 6 or more years of rotating night shifts.
Longer durations of shift work may significantly increase cardiovascular risk in women.
GoodSupportsmedium confidence
The multivariate adjusted relative risks of CHD were 1.51 (95% CI, 1.12 to 2.03) among those reporting 6 or more years of rotating night shifts.
Why this rating
Based on a prospective cohort study design.
Source
Prospective Study of Shift Work and Risk of Coronary Heart Disease in Women
Ichiro Kawachi et al. · Circulation · 1995
DOI 10.1161/01.cir.92.11.3178
cohort · n=79109Cited 528×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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- Women who reported ever doing shift work had an age-adjusted relative risk of coronary heart disease (CHD) of 1.38 compared to those who had never done shift work.Good
- The excess risk of CHD associated with shift work persisted after adjustment for cigarette smoking and other cardiovascular risk factors.Good
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