Research
Hormonal
No substantial associations were found with percent free or percent bioavailable estradiol, androstenedione, testosterone, or dehydroepiandrosterone.
Practitioners should note that not all hormone levels are associated with breast cancer risk, particularly those mentioned.
StrongRefutesmedium confidence
We found no substantial associations with percent free or percent bioavailable estradiol, androstenedione, testosterone, or dehydroepiandrosterone.
Why this rating
Based on the prospective evaluation within a large cohort study.
Source
Plasma Sex Steroid Hormone Levels and Risk of Breast Cancer in Postmenopausal Women
Susan E. Hankinson et al. · JNCI Journal of the National Cancer Institute · 1998
DOI 10.1093/jnci/90.17.1292
case_control · n=11169Cited 690×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
- Higher circulating levels of estradiol are associated with an increased risk of breast cancer in postmenopausal women (multivariate RR = 1.91; 95% CI = 1.06-3.46).Strong
- Higher levels of estrone, estrone sulfate, and dehydroepiandrosterone sulfate are also associated with increased breast cancer risk.Strong
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