Research
Hormonal
A new approach via personalized therapy adaptations must be applied to target beneficial effects on complications as well as on body weight management.
Tailoring exercise and nutrition strategies can improve health outcomes for individuals with type 1 diabetes.
StrongSupportsmedium confidence
A new approach via personalized therapy adaptations must be applied to target beneficial effects on complications as well as on body weight management.
Why this rating
The review emphasizes the importance of personalized approaches based on recent findings.
Source
Type 1 Diabetes and Physical Exercise: Moving (forward) as an Adjuvant Therapy
Othmar Moser et al. · Current Pharmaceutical Design · 2020
DOI 10.2174/1381612826666200108113002
reviewCited 37×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
- Physical exercise has several positive effects on glucose uptake and systemic inflammation in adults with type 1 diabetes.Strong
- Adults with type 1 diabetes can expect similar physiological responses to physical exercise as seen in their healthy counterparts when combined with pre-defined macronutrient intake around exercise.Strong
Related findings · Hormonal
- Initial treatment for type 2 diabetes should be a combination of metformin and either an SGLT-2 inhibitor or a GLP-1 receptor agonist to achieve cardiorenal protection, rather than monotherapy or older agents like sulfonylureas.Strong
- For patients with specific monogenic obesity syndromes (leptin deficiency, POMC/PCSK1/LEPR mutations), targeted pharmacotherapy (recombinant leptin or setmelanotide) is highly effective and should be prioritized, unlike in polygenic obesity.Strong
- Continued weekly administration of 2.4 mg subcutaneous semaglutide prevents weight regain and promotes further weight loss in adults with overweight or obesity, whereas switching to placebo results in significant weight regain.Strong
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