Hormonal
Initiating combination therapy at the time of diagnosis for Type 2 Diabetes is scientifically supported to improve durability of glycaemic control and reduce complications, yet is underutilized due to 'clinical inertia'.
If your blood sugar is high at diagnosis, do not accept being put on just one medication if your doctor suggests it might not be enough. The paper argues that starting with a combination of drugs early on is scientifically better for long-term control and prevents complications. Ask your doctor why combination therapy isn't being used if your levels are high. Do not let 'clinical inertia' (delaying treatment) prevent you from getting the best possible control from the start.
The use of combination therapy at diagnosis could positively influence the durability of glycaemic control, changes in insulin sensitivity and β-cell function, time to insulin introduction, influences diabetic complications and the effects on some surrogates.
Why this rating
Based on guidelines and cited trials (e.g., VERIFY trial) referenced in the discussion, though the survey itself is observational.
Source
Understanding the barriers and improving care in type 2 diabetes: Brazilian perspective in time to do more in diabetes
Sérgio Vencio et al. · Diabetology & Metabolic Syndrome · 2017
DOI 10.1186/s13098-017-0244-y
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