Research
Hormonal
Ghrelin and leptin are not responsible for the satiating effect of chocolate products.
Practitioners should consider that chocolate may not influence appetite through ghrelin and leptin.
StrongRefutesmedium confidence
It appears that ghrelin and leptin are not responsible for the satiating effect of chocolate products.
Why this rating
Based on systematic review methodology.
Source
The effect of chocolate-based products on some appetite-related hormones: a systematic review
Zahra Shirzadi et al. · International Journal of Food Sciences and Nutrition · 2020
DOI 10.1080/09637486.2020.1734543
Meta-analysisCited 1×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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