Research

Macro partitioning

Caloric restriction alone in older adults with sarcopenic obesity leads to significant loss of lean muscle mass and grip strength, worsening sarcopenia.

If you are an older adult with obesity, simply eating less (caloric restriction) without exercise can cause you to lose muscle, not just fat. This makes you weaker and more frail. To avoid this, you must combine dietary changes with resistance exercise and ensure you are eating enough protein.

GoodRefutesHIGH confidence
Meta-analysis [21] of 33 intervention studies lasting 8–24 weeks reported that calorie restriction alone without resistance training leads to the loss of muscle mass and loss of handgrip strength
Ondřej Žižka et al. · Drugs & Aging · 2024

Why this rating

Based on a meta-analysis of 33 studies and a specific RCT cited.

Source

Pharmacological Treatment of Obesity in Older Adults

Ondřej Žižka et al. · Drugs & Aging · 2024

narrative_reviewCited 16×
Read the paper

This is one finding among thousands. Every one is graded and traced to its source, so you can see what the evidence actually supports. Browse the research →