Hormonal
Weight loss in Type 2 Diabetic patients releases Persistent Organic Pollutants (POPs) from adipose tissue into circulation, which can attenuate or negate the expected cardiovascular benefits of the weight loss.
If you have Type 2 Diabetes and are losing weight, be aware that fat loss releases stored environmental chemicals (POPs) into your blood, which might temporarily offset heart health benefits. To mitigate this, focus on dietary strategies that help your body excrete these toxins, such as a plant-based diet with moderate fat and intermittent fasting, rather than just any weight loss method.
persistent organic pollutants (POPs) released from adipose during weight loss in type 2 diabetic (T2DM) patients may attenuate cardiovascular (CV) benefits[1] that should accompany >5% weight reduction and concomitant fall in CV disease risk factors.[2]
Why this rating
The paper is an opinion/commentary citing epidemiological evidence and mechanistic studies, not a primary clinical trial.
Source
Weight Loss Strategies for Type 2 Diabetic Patients: Can Dietary Interventions That Reduce Circulating Persistent Organic Pollutants Improve Cardiovascular Outcomes?
Kimberley A. Bennett · BioEssays · 2020
DOI 10.1002/bies.202000069
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