Hormonal
Metabolic and bariatric surgery (MBS) shows a trend toward reducing MACE risk compared to both medical weight management and usual care in patients with obesity and type 2 diabetes, potentially due to metabolic changes independent of weight loss.
Bariatric surgery showed a trend toward reducing heart events compared to usual care or medical weight management in this study. This benefit might come from metabolic changes, not just weight loss. If you are considering surgery, discuss these potential cardiovascular benefits with your healthcare provider, especially if you have type 2 diabetes.
We did find a trend showing that those who underwent MBS had a lower risk of MACE events compared to those receiving MWM or UC (both p=0.06)... it may also be possible that MACE reduction following MBS may not be entirely weight loss dependent but also due to metabolic changes that occur following MBS.
Why this rating
Retrospective cohort study; p-value was 0.06 (trend, not significant); limited follow-up.
Source
Major Adverse Cardiovascular Event Outcomes in Patients With Obesity and Type 2 Diabetes Undergoing Medical Weight Management
Nirjhar Dutta et al. · Cureus · 2025
DOI 10.7759/cureus.94070
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