Research
Macro partitioning
In men, higher intake of total fat, saturated fatty acids (SFA), monounsaturated fatty acids (MUFA), and n-6 fatty acids is associated with decreased all-cause mortality.
If you are a man over 40, ensuring adequate intake of fats, including saturated and monounsaturated fats (from sources like meat, cheese, nuts), may support longevity. This does not mean overconsumption, but rather that fat restriction may not be necessary for men in the same way it is often recommended.
GoodQualifiesHIGH confidence
In men, negative correlations were observed between the following nutrient intakes and mortality: total fat (OR: 0.963; 95%CI: 0.934–0.993; p = 0.017), SFA (OR: 0.866; 95%CI: 0.783–0.957; p = 0.005), MUFA (OR: 0.909; 95%CI: 0.839–0.984; p = 0.019), and n-6 fatty acids (OR: 0.854; 95%CI: 0.734–0.994; p = 0.042).
Why this rating
Longitudinal cohort study, but observational nature limits causal inference.
Source
Sex Differences in the Relationship Between Nutrient Intake and Mortality Results of the Shika Cohort Study
K Hayashi et al. · Nutrients · 2025
cohort · n=3743
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