Macro partitioning
Substituting Polyunsaturated Fatty Acids (PUFA) for carbohydrates (LGI or HGI) significantly reduces the odds of developing hypertension.
To potentially lower your risk of developing hypertension, consider replacing 3% of your daily calories from carbohydrates (both low and high glycemic index) with Polyunsaturated Fats (PUFA). This is particularly beneficial for women in this study. Ensure you keep your total calorie intake the same by reducing carbs rather than adding extra fat. Good sources of PUFA include fatty fish, walnuts, and sunflower oil.
Substituting 3% of the energy intake of PUFA in place of different types of carbohydrates was associated with lower odds of hypertension.
Why this rating
Longitudinal data with robust statistical modeling (GEE), but observational nature limits causal claims.
Source
Dietary Fats Substitution and Blood Pressure Levels: A Longitudinal Study in Mexican Adults
Paola Villaverde et al. · Nutrients · 2025
DOI 10.3390/nu17132096
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