Macro partitioning

Moderate adherence to a nutrient pattern rich in unsaturated fatty acids and vitamin E is associated with lower all-cause and cancer mortality, whereas high adherence is associated with increased cerebrovascular disease mortality.

Include unsaturated fats (like those in fish and vegetable oils) and vitamin E sources in your diet, but avoid excessive consumption. The study suggests that moderate intake lowers cancer and all-cause mortality, while very high intake might increase stroke risk, possibly due to how these fats are prepared (e.g., deep-frying) or paired with other high-fat foods.