Research
Hormonal
Obesity negatively impacts asthma outcomes and has a causal link in the pathogenesis of adult-onset asthma, primarily through a pro-inflammatory state driven by an imbalance in the adipose organ.
If you have obesity and asthma, your excess fat tissue is actively creating inflammation that makes your asthma worse. This is not just about being less active; it is a biological mechanism. Weight loss, even without surgery, can reduce this inflammation and improve asthma control.
GoodSupportsHIGH confidence
Obesity negatively impacts asthma outcomes and has a causal link in the pathogenesis of adult-onset asthma. Imbalance in the adipose organ found in obesity favours a pro-inflammatory state both systemically and in airways.
Why this rating
Supported by multiple large cohort studies and genome-wide association studies cited in the review.
Source
Obesity, Inflammation, and Severe Asthma: an Update
Varun Sharma et al. · Current Allergy and Asthma Reports · 2021
DOI 10.1007/s11882-021-01024-9
narrative_reviewCited 109×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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