Hormonal
Laparoscopic sleeve gastrectomy significantly reduces plasma Total Antioxidant Capacity (TAC), Total Oxidant Status (TOS), and DPPH radical-scavenging activity in morbidly obese patients over a 12-month period, indicating a restoration of redox homeostasis.
For morbidly obese individuals, bariatric surgery like sleeve gastrectomy significantly improves the body's antioxidant and oxidant balance over the first year, potentially reducing long-term health risks associated with oxidative stress. This benefit is achieved alongside strict adherence to post-operative dietary guidelines, including caloric restriction and specific vitamin supplementation.
Total antioxidant capacity (TAC), ferric-reducing antioxidant power (FRAP), DPPH (2,2-diphenyl-1-picrylhydrazyl) radical assay, and total oxidant status (TOS) were significantly higher before surgery (as compared to the healthy controls, n = 60) and generally decreased after bariatric treatment.
Why this rating
Longitudinal study with 60 patients, clear pre/post measurements, and statistical significance, but lacks a non-surgical control group for weight loss alone.
Source
Impact of Weight Loss on the Total Antioxidant/Oxidant Potential in Patients with Morbid Obesity—A Longitudinal Study
Barbara Choromańska et al. · Antioxidants · 2020
DOI 10.3390/antiox9050376
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