Research
Macro partitioning
Trans-fatty acids (TFAs) increase the risk of coronary heart disease and sudden death more strongly than any other nutrient, primarily by raising LDL cholesterol and lowering HDL cholesterol.
Avoid trans-fatty acids completely. They are found in partially hydrogenated oils used in many processed foods. A 2% increase in energy from TFAs is linked to a 23% higher risk of heart disease. Check labels for 'partially hydrogenated oils' and avoid these products entirely.
StrongSupportsVERY_HIGH confidence
Data in the literature are very consistent in showing that TFA intake is associated with a higher risk of CVD and sudden death; this relationship is stronger than with any other nutrient... a 2% increase in energy intake from TFAs is associated with a 23% higher incidence of coronary heart disease (CHD)
Why this rating
Described as 'very consistent' in literature with meta-analyses of prospective cohort studies showing strong associations.
Source
Diet, Lifestyle, Smoking
Lâle Tokgözoğlu et al. · Handbook of experimental pharmacology · 2020
book_chapterCited 14×
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