Hormonal
Dapagliflozin (5-10 mg) significantly improves glycemic control (HbA1c reduction) in Type 2 Diabetes patients over 12 months with a favorable safety profile, despite a small risk of genital infections and rare DKA.
If you have Type 2 Diabetes, Dapagliflozin (5-10mg daily) is an effective, well-tolerated option to lower your HbA1c. It works by helping your kidneys excrete excess sugar. While it slightly increases the risk of genital itching or yeast infections, serious side effects are rare. It is often used alongside diet, exercise, and other diabetes medications.
Dapagliflozin was found to be a well tolerated and effective treatment option for T2DM patients in Saudi Arabia... The mean (SD) HbA1c% level significantly decreased from 8.6 (1.6) % at baseline to reach 7.2 (1.2) % after 12 months of treatment (p < 0.0001).
Why this rating
Single-arm, non-interventional, real-world post-marketing study (PASS) without a control group; prone to bias but reflects real-world efficacy.
Source
Safety of Dapagliflozin in Patients with Type 2 Diabetes Mellitus in Saudi Arabia: A Post Authorization Safety Study
Abdullah M. Alguwaihes · Diabetes Therapy · 2021
DOI 10.1007/s13300-021-01092-0
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