Research
Macro partitioning
Orlistat (60mg OTC or 120mg Rx) is a pharmacological option that reduces fat absorption but has significant gastrointestinal side effects (steatorrhea) that can be managed through patient education.
Orlistat (60mg OTC, 120mg Rx) inhibits fat absorption. It is less effective than GLP-1s. Key to adherence is educating patients to eat a low-fat diet to avoid steatorrhea. It is an adjunct to lifestyle changes.
GoodQualifiesHIGH confidence
L’orlistat est un inhibiteur de la lipase pancréatique, qui induit une réduction de l’absorption intestinale des graisses. Son effet secondaire principal, les diarrhées graisseuses, peut être évité grâce à une approche pédagogique.
Why this rating
Described in guidelines and consensus statements.
Source
Comment prendre en charge l’obésité au cabinet d’un médecin généraliste ?
Serpil Berkcan et al. · Archive ouverte UNIGE (University of Geneva) · 2022
narrative_reviewCited 1×
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