Research
Hormonal
Jatobá-do-cerrado polyphenol extracts reduce glucose uptake and downregulate the gene expression of glucose transporters SGLT1 and GLUT2 in Caco-2 cells in a dose-dependent manner.
Lab studies show that jatobá polyphenols can reduce how intestinal cells absorb glucose and lower the expression of key glucose transporters. This suggests a potential mechanism for blood sugar control, but human studies are needed to confirm this effect.
ModerateSupportsMEDIUM confidence
Os extratos também demonstraram inibir significativamente tanto a captação de glicose independente de sódio quanto a expressão gênica dos transportadores de glicose SGLT1 e GLUT2 de maneira dose-dependente.
Why this rating
In vitro study on Caco-2 cells; lacks human clinical validation.
Source
Bioacessibilidade dos polifenóis do jatobá-do-cerrado (Hymenaea Stigonocarpa Mart.) e seus efeitos em genes relacionados à absorção de glicose em células Caco-2
C.P. Silva · 2018
DOI 10.11606/t.6.2018.tde-24042018-125449
mechanism_only
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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