Hormonal
Targeting a follow-up HbA1c level below 7.0% fails to maximize cardiovascular benefits and may increase the risk of heart failure and non-fatal stroke compared to maintaining levels above 7.0%.
If you have Type 2 Diabetes, aiming for an HbA1c below 7.0% may not provide the best cardiovascular protection and could increase your risk of heart failure. Current evidence suggests that maintaining levels slightly above 7.0% might offer better protection against major cardiovascular events. Discuss your specific cardiovascular risk profile with your doctor to determine the safest target.
HbA1c below 7.0 % as the goal to maximize the cardiovascular benefits remains suspended... controlling HbA1c below 7.0 % could not maximize the cardiovascular benefits, and the disadvantages outweigh the advantages.
Why this rating
Large-scale meta-analysis of 15 RCTs with 88,266 patients, though heterogeneity exists in heart failure outcomes.
Source
HbA1c below 7 % as the goal of glucose control fails to maximize the cardiovascular benefits: a meta-analysis
Pin Wang et al. · Cardiovascular Diabetology · 2015
DOI 10.1186/s12933-015-0285-1
Related findings · Hormonal
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