Research
Hormonal
For individuals with type 2 diabetes, a Mediterranean diet provides superior glycemic control (fasting glucose and insulin sensitivity) compared to a low-fat diet.
If you have type 2 diabetes, a Mediterranean diet may help control your blood sugar better than a standard low-fat diet. This diet emphasizes vegetables, olive oil, and nuts, and limits red meat. In this study, it significantly improved insulin sensitivity and lowered fasting glucose in diabetic participants, whereas a low-fat diet did not.
StrongQualifiesHIGH confidence
Among the 36 subjects with diabetes, changes in fasting plasma glucose and insulin levels were more favorable among those assigned to the Mediterranean diet than among those assigned to the low-fat diet (P<0.001 for the interaction among diabetes and Mediterranean diet and time with respect to fasting glucose levels).
Why this rating
RCT with specific subgroup analysis showing significant interaction.
Source
Weight Loss with a Low-Carbohydrate, Mediterranean, or Low-Fat Diet
Iris Shai et al. · New England Journal of Medicine · 2008
DOI 10.1056/nejmoa0708681
rct · n=322Cited 2,127×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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