Research

Macro partitioning

Low-carbohydrate diets (5-25% energy from carbohydrate) improve cardiometabolic markers (weight, HDL, triglycerides) in healthy adults over 12 weeks, with greater carbohydrate restriction yielding larger improvements in HDL and triglycerides.

Adopting a low-carbohydrate diet (5-25% of calories from carbs) for 12 weeks can improve your weight, waist size, and key blood markers like HDL and triglycerides, even if you don't change your total calorie intake. While stricter diets (5% carbs) yield the best blood marker improvements, moderate restriction (15-25% carbs) is easier to stick to and still provides significant health benefits.

ModerateSupportsMEDIUM confidence
LCHF diets have a positive effect on markers of health... there were comparable improvements in weight loss and waist circumference and greater improvements in HDL-c and TG with greater carbohydrate restriction.
Cliff Harvey et al. · 2019

Why this rating

Randomized controlled trial design, but limited by high attrition (49% dropout) and small final sample size (n=39).

Source

Peer Review #1 of "Low-carbohydrate diets differing in carbohydrate restriction improve cardiometabolic and anthropometric markers in healthy adults: A randomised clinical trial (v0.1)"

Cliff Harvey et al. · 2019

DOI 10.7287/peerj.6273v0.1/reviews/1

rct · n=77
Read the paper
DOI resolved against Crossref · corpus check 2026-06-10

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