Macro partitioning
High intake of saturated fat is not associated with increased risk of all-cause mortality, cardiovascular disease, coronary heart disease, ischemic stroke, or type 2 diabetes when compared to low intake.
Current observational evidence does not support the idea that eating saturated fat directly causes heart disease or death. However, the quality of this evidence is very low, meaning future research could change these conclusions. Focus on what you replace saturated fat with, as the source of replacement nutrients matters significantly.
Saturated fat intake was not associated with all cause mortality (relative risk 0.99, 95% confidence interval 0.91 to 1.09), CVD mortality (0.97, 0.84 to 1.12), total CHD (1.06, 0.95 to 1.17), ischemic stroke (1.02, 0.90 to 1.15), or type 2 diabetes (0.95, 0.88 to 1.03).
Why this rating
The study is a systematic review and meta-analysis of observational studies, but the authors rate the certainty of evidence as 'very low' due to inconsistency and methodological limitations.
Source
Intake of saturated and trans unsaturated fatty acids and risk of all cause mortality, cardiovascular disease, and type 2 diabetes: systematic review and meta-analysis of observational studies
Russell J. de Souza et al. · BMJ · 2015
DOI 10.1136/bmj.h3978
Related findings · Macro partitioning
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