Hormonal
Bariatric surgery significantly increases the likelihood of long-term remission of type 2 diabetes compared to non-surgical management, with remission rates remaining higher than controls even after 15 years.
For individuals with obesity and type 2 diabetes, bariatric surgery offers a high probability of long-term diabetes remission compared to non-surgical management. While remission rates decline over time, they remain significantly higher than those not undergoing surgery, and the procedure is also associated with reduced macrovascular and microvascular complications.
At 2 years, a greater proportion of people in the surgery group were in diabetes remission than in the control group (72.3% vs. 16.4%; unadjusted odds ratio 13·3, 95% CI 8·5–20·7). At 15 years follow-up, the proportion of patients in the surgery group who were in remission decreased (30·4%), but these patients were still more likely to be in remission than were those in the control group (odds ratio 6·3, 95% CI 2·1–18.9).
Why this rating
Based on a large observational cohort (Swedish Obese Study) with long-term follow-up, though not a randomized controlled trial.
Source
Association of Bariatric Surgery With Long-term Remission of Type 2 Diabetes and With Microvascular and Macrovascular Complications
Lars Sjöström et al. · JAMA · 2014
DOI 10.1001/jama.2014.5988
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