Research
Hormonal
Postmenopausal weight loss of 10 kg or more, particularly when maintained, significantly decreases the risk of breast cancer in women who have never used postmenopausal hormones.
If you are postmenopausal and have never used hormone therapy, losing 10 kg or more and keeping it off can significantly lower your risk of breast cancer. This benefit is particularly strong for those who have never used postmenopausal hormones.
StrongSupportsHIGH confidence
Women who had never used postmenopausal hormones, lost 10.0 kg or more since menopause, and kept the weight off were at a lower risk than those who maintained weight (RR, 0.43; 95% CI, 0.21-0.86; P = .01 for weight loss trend).
Why this rating
Large prospective cohort study with long follow-up and rigorous adjustment for confounders.
Source
Adult Weight Change and Risk of Postmenopausal Breast Cancer
A. Heather Eliassen et al. · JAMA · 2006
cohort · n=87143Cited 650×
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