Research
Hormonal
Obesity (BMI ≥30 kg/m²) is a major risk factor for the development, recurrence, and mortality of several solid-organ and hematological malignancies, including post-menopausal breast, colorectal, endometrial, kidney, esophageal, pancreatic, liver, and gallbladder cancers.
Maintaining a healthy body weight (BMI <25) is a critical strategy for reducing the risk of developing several common cancers, particularly post-menopausal breast, colorectal, and endometrial cancers. For cancer survivors, weight management is essential to reduce the risk of recurrence and improve survival outcomes.
StrongSupportsHIGH confidence
Obesity is a risk factor for several major cancers, including post-menopausal breast, colorectal, endometrial, kidney, esophageal, pancreatic, liver, and gallbladder cancer.
Why this rating
Based on large population-based studies (5.24 million individuals), Mendelian randomization, and umbrella reviews of systematic reviews.
Source
Obesity and Cancer: A Current Overview of Epidemiology, Pathogenesis, Outcomes, and Management
Sukanya Pati et al. · Cancers · 2023
narrative_reviewCited 604×
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