Hormonal
Once-weekly semaglutide 2.4 mg delivers significant weight loss (approx. 15-16% in non-diabetics, 9.6% in diabetics) and improves cardiovascular risk factors, and is FDA-approved for chronic weight management in adults with BMI ≥30 kg/m2 or ≥25 kg/m2 with comorbidities.
If you have type 2 diabetes and struggle with weight, once-weekly semaglutide 2.4 mg is a highly effective, FDA-approved option. It can lead to nearly 10% body weight loss when combined with lifestyle changes. While you may experience some gastrointestinal side effects, most people tolerate it well enough to stay on the medication, which is crucial for maintaining the weight loss and improving heart health markers.
Thus, once weekly semaglutide 2.4 mg delivers impressive weight loss and cardiovascular risk factor improvement and is FDA approved for chronic weight management in adults with BMI ≥30 kg/m2 or BMI ≥25 kg/m2 with a comorbid condition (ie, T2D, hypertension, hyperlipidemia).
Why this rating
Based on multiple large randomized controlled trials (STEP 1, 2, 3, 4) with consistent results.
Source
Comprehensive Management of Cardiovascular Risk Factors for Adults With Type 2 Diabetes: A Scientific Statement From the American Heart Association
Joshua J. Joseph et al. · Circulation · 2022
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