Macro partitioning
Higher dietary intake of linoleic acid (LA) is inversely associated with the risk of coronary heart disease (CHD) events and CHD deaths in a dose-response manner.
Increase your intake of linoleic acid by choosing vegetable oils (like sunflower, safflower, soy, corn) and nuts instead of saturated fats (like butter, lard, or fatty meats). This substitution is associated with a lower risk of heart disease events and death. You do not need to fear linoleic acid causes inflammation; current evidence supports its cardiovascular benefits when used to replace saturated fats.
In prospective observational studies, dietary LA intake is inversely associated with CHD risk in a dose-response manner.
Why this rating
Systematic review and meta-analysis of 13 prospective cohort studies with over 300,000 individuals, though observational design limits causal inference compared to RCTs.
Source
Dietary Linoleic Acid and Risk of Coronary Heart Disease: A Systematic Review and Meta-Analysis of Prospective Cohort Studies
Maryam S. Farvid et al. · Circulation · 2014
DOI 10.1161/circulationaha.114.010236
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