Research
Macro partitioning
High dietary glycemic load is strongly associated with an increased risk of coronary heart disease in women.
Focus on the quality and quantity of carbohydrates. High glycemic load foods (those that spike blood sugar significantly) are linked to nearly double the risk of heart disease. Choosing lower glycemic load carbohydrates helps mitigate this risk.
GoodSupportsHIGH confidence
A higher glycemic load was strongly associated with an increased risk of coronary heart disease (relative risk comparing highest and lowest deciles, 1.90; 95% CI, 1.15 to 3.15; P for trend = 0.003).
Why this rating
Same high-quality cohort data as N1, statistically significant trend.
Source
Low-Carbohydrate-Diet Score and the Risk of Coronary Heart Disease in Women
Thomas L. Halton et al. · New England Journal of Medicine · 2006
DOI 10.1056/nejmoa055317
cohort · n=82802Cited 516×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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