Research
Macro partitioning
Trans-fatty acids from partially hydrogenated oils have the most adverse health effects on a gram-for-gram basis, increasing LDL, decreasing HDL, and raising CHD risk more than saturated fats.
Avoid foods containing partially hydrogenated oils, as they contain industrial trans fats which are highly harmful to heart health. Check nutrition labels for this ingredient. Natural trans fats in small amounts from animal products are not the primary concern.
StrongSupportsHIGH confidence
On a gram-for-gram basis, trans–fatty acids have the most adverse health effects. Trans fat increases LDL and decreases HDL (8), raises the proportion of small, dense, and atherogenic LDL particles (101), raises Lp(a) (117, 126), and increases inflammatory markers that have been related to CHD risk (10, 121).
Why this rating
Supported by prospective studies, metabolic studies, and regulatory actions cited in the review.
Source
Current Evidence on Healthy Eating
Walter C. Willett et al. · Annual Review of Public Health · 2013
narrative_reviewCited 251×
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