Research
Hormonal
High sodium intake (>5 g/d) increases cardiovascular risk primarily in individuals with hypertension, whereas in normotensive individuals, the risk increase is less prominent or occurs only at much higher levels.
If you have high blood pressure, keeping your sodium intake below 5 grams per day is crucial to avoid increased cardiovascular risk. For those with normal blood pressure, the risk from high sodium may be lower, but moderation is still advised.
GoodQualifiesHIGH confidence
The increased risk of cardiovascular events associated with higher sodium intake (>5 g/d) is most prominent in those with hypertension.
Why this rating
Based on large cohort studies (PURE) showing significant interaction between hypertension and sodium intake.
Source
Sodium Intake and Cardiovascular Health
Martin O’Donnell et al. · Circulation Research · 2015
DOI 10.1161/circresaha.116.303771
narrative_reviewCited 206×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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