Adherence
Cohort unrepresentativeness in the UK Biobank leads to an underestimation of the mortality risk associated with the least healthy cumulative lifestyle profiles.
If you have an unhealthy lifestyle (poor diet, low activity, smoking), the risk to your life is likely higher than general statistics suggest. Correcting for population biases shows a 9% increase in mortality risk for the least healthy groups. Prioritize improving these factors to mitigate this hidden risk.
The magnitude of the poststratified all-cause mortality hazard ratio comparing least healthy with healthiest tertile of lifestyle risk factor index was 9% higher (95% confidence interval: 4%, 14%) than the unweighted estimates.
Why this rating
Robust statistical correction and large sample size, but observational nature prevents definitive causal claims about specific lifestyle combinations.
Source
Is Cohort Representativeness Passé? Poststratified Associations of Lifestyle Risk Factors with Mortality in the UK Biobank
Emmanuel Stamatakis et al. · Epidemiology · 2021
This is one finding among thousands. Every one is graded and traced to its source, so you can see what the evidence actually supports. Browse the research →