Macro partitioning
Intravenous amino acid infusion improves muscle protein synthesis and reduces perioperative blood loss in total joint arthroplasty patients.
If your surgical team recommends intravenous amino acids during your joint replacement, it may help preserve muscle protein and reduce blood loss. This is a specific medical intervention that complements your surgery, not a substitute for post-operative nutrition.
Intravenous amino acid infusion improved muscle protein synthesis and reduced perioperative blood loss.
Why this rating
Based on 5 studies using IV intervention, but findings are mixed regarding other outcomes like blood pressure and temperature.
Source
Peri-operative protein or amino acid supplementation for total joint arthroplasty: a systematic review and meta-analysis
Yashar Khani et al. · Journal of Orthopaedic Surgery and Research · 2025
DOI 10.1186/s13018-025-05847-4
More from this paper
- Peri-operative essential amino acid (EAA) supplementation significantly reduces muscle atrophy in quadriceps and hamstring muscles following total joint arthroplasty.Good
- Peri-operative protein or amino acid supplementation does not significantly improve muscle strength (quadriceps or handgrip) or functional outcomes in total joint arthroplasty patients.Good
Related findings · Macro partitioning
- Total daily protein intake of 1.6 g/kg/day is sufficient for maximizing resistance training-induced muscle gains, with an upper confidence interval of 2.2 g/kg/day.Strong
- Resistance exercise training combined with sufficient dietary protein intake acts synergistically to maximize skeletal muscle hypertrophy, with protein intake saturating around 1.6 g/kg/day for general populations and potentially requiring 2.0-2.2 g/kg/day for resistance-trained individuals.Strong
- Trans fats should be completely eliminated from the diet, as they increase LDL cholesterol, decrease HDL cholesterol, and are directly associated with increased coronary risk.Strong
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