Research
Hormonal
Metabolically healthy obesity (MHO) is a transient phenotype that often transitions to metabolically unhealthy obesity with aging, and MHO individuals still face increased risks for heart failure and non-metabolic comorbidities.
Being 'metabolically healthy' now does not mean you are immune to future metabolic disease. Your risk of developing diabetes or heart issues increases as you age, even if you are currently healthy. Regular monitoring and maintaining a healthy lifestyle are essential to delay or prevent this transition.
GoodQualifiesHIGH confidence
The BioShare-EU project also demonstrated that the prevalence of MHO significantly decreases with age in both genders... These data are at least suggestive for the hypothesis that MHO represents a transient phenotype.
Why this rating
Based on large prospective cohort studies (BioShare-EU, Pizarra).
Source
MECHANISMS IN ENDOCRINOLOGY: Are metabolically healthy obese individuals really healthy?
Matthias Blüher · European Journal of Endocrinology · 2014
DOI 10.1530/eje-14-0540
narrative_reviewCited 168×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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