Adherence
Weight loss interventions, including lifestyle changes and ACE inhibition, can reduce blood pressure, glomerular hyperfiltration, and proteinuria in obese patients with CKD.
If you have kidney disease and are overweight, losing weight can help your kidneys by lowering blood pressure and reducing protein leakage. Talk to your doctor about a safe weight loss plan, which may include diet changes, exercise, and medications like ACE inhibitors. In advanced kidney disease, the approach needs to be very careful to avoid malnutrition.
In a recent meta-analysis collating experimental studies in obese CKD patients, interventions aimed at reducing bodyweight showed coherent reductions in blood pressure, glomerular hyperfiltration and proteinuria.
Why this rating
Based on a meta-analysis of experimental studies and post-hoc analyses, but the paper notes a paucity of high-level evidence intervention studies.
Source
Obesity and kidney disease: hidden consequences of the epidemic
Csaba P. Kövesdy et al. · Journal of Endocrinology Metabolism and Diabetes of South Africa · 2017
DOI 10.1080/16089677.2017.1299975
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