Adherence
High baseline cardiorespiratory fitness (CRF) is independently associated with a significantly lower risk of incident heart failure (HF), particularly heart failure with preserved ejection fraction (HFpEF), in adults with type 2 diabetes.
For adults with type 2 diabetes, prioritizing cardiorespiratory fitness (CRF) is more critical for preventing heart failure than focusing solely on weight loss. Aim to improve your aerobic capacity through regular physical activity, as higher fitness levels are strongly linked to a reduced risk of heart failure, particularly the preserved ejection fraction subtype.
In the most adjusted Cox models, the risk of HF was 39% and 62% lower among moderate fit (tertile 2: hazard ratio, 0.61 [95% CI, 0.44–0.83]) and high fit (tertile 3: hazard ratio, 0.38 [95% CI, 0.24–0.59]) groups, respectively (referent group: low fit, tertile 1)... the risk of incident HF with preserved ejection fraction was 40% lower in the moderate fit group and 77% lower in the high fit group.
Why this rating
Large randomized trial (Look AHEAD) with long-term follow-up and adjudicated outcomes.
Source
Association of Intensive Lifestyle Intervention, Fitness, and Body Mass Index With Risk of Heart Failure in Overweight or Obese Adults With Type 2 Diabetes Mellitus
Ambarish Pandey et al. · Circulation · 2020
DOI 10.1161/circulationaha.119.044865
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