Hormonal
Two weeks of acute physical inactivity (step count <1,000/day) causes a significant decline in glycemic control and integrated muscle protein synthesis in overweight, prediabetic older adults, and these metabolic impairments fail to recover after two weeks of returning to habitual activity levels.
If you are an older adult with prediabetes, even a short period of reduced activity (fewer than 1,000 steps a day) can worsen your blood sugar control and muscle building processes. Crucially, simply going back to your normal activity level for two weeks may not be enough to fix these issues. You may need to be more proactive, such as engaging in specific exercise or medical management, to prevent these declines and help your body recover faster after periods of inactivity.
Our findings demonstrate that 2 wk of SR leads to lowered rates of muscle protein synthesis and a worsening of glycemic control that unlike younger adults is not recovered during return to normal activity in overweight, prediabetic elderly humans.
Why this rating
Randomized controlled trial design with a clear intervention and recovery phase, though limited by a small sample size (n=22) and short duration.
Source
Failed Recovery of Glycemic Control and Myofibrillar Protein Synthesis With 2 wk of Physical Inactivity in Overweight, Prediabetic Older Adults
Chris McGlory et al. · The Journals of Gerontology Series A · 2017
DOI 10.1093/gerona/glx203
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