Hormonal
Aging causes 'anabolic resistance,' characterized by a blunted muscle protein synthesis response to feeding, which contributes to sarcopenia.
As you age, your body becomes less efficient at turning food into muscle (anabolic resistance). To combat this, you likely need to consume slightly more protein per meal or ensure you are doing resistance exercise to 'wake up' the muscle's synthetic machinery.
In states such as aging, there is an anabolic resistance to feeding, which is characterized by a blunted rise of MPS to amino acids.
Why this rating
Supported by multiple citations (Cuthbertson et al. 2005; Guillet et al. 2004) in a peer-reviewed review.
Source
Physiologic and molecular bases of muscle hypertrophy and atrophy: impact of resistance exercise on human skeletal muscle (protein and exercise dose effects)This paper is one of a selection of papers published in this Special Issue, entitled 14th International Biochemistry of Exercise Conference – Muscles as Molecular and Metabolic Machines, and has undergone the Journal’s usual peer review process.
Stuart M. Phillips · Applied Physiology Nutrition and Metabolism · 2009
DOI 10.1139/h09-042
More from this paper
- Resistance exercise is a potent stimulator of muscle protein synthesis (MPS) that acts synergistically with protein feeding to counteract age-related and disuse-induced muscle loss.Good
- Leucine is a critical amino acid that can stimulate muscle protein synthesis, but complete essential amino acids are required for sustained MPS.Good
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