Macro partitioning
The source of fat and protein in a low-carbohydrate diet matters: vegetable-based LCD scores are associated with reduced T2D risk in men, whereas animal-based LCD scores show no significant association with risk reduction.
If you are a Japanese man considering a low-carb diet, prioritize vegetable fats (like those from fish, nuts, and seeds) and vegetable proteins. This specific combination was linked to a significantly lower risk of type 2 diabetes. Simply cutting carbs and eating animal fats/proteins did not show the same benefit in this study.
The vegetable LCD score was associated with a lower risk of T2D in men (OR 0.51; 95 % CI 0.33, 0.77)... The multivariable-adjusted OR of incident T2D for the highest v. lowest quintiles of... animal LCD scores... were... 0·83 (95 % CI 0.55, 1.27) for men.
Why this rating
Observational data; relies on self-reported FFQ; significant sex difference not found in women.
Source
Association between low-carbohydrate diet score and incidence of type 2 diabetes among Japanese adults: the JACC Study
Akinori Yaegashi et al. · Journal of Nutritional Science · 2023
DOI 10.1017/jns.2022.122
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